RAF Typhoon FGR4s have operated alongside French aircraft in a combined operation against an subterranean weapons facility in Syria used by the IS group, per a report from the UK Ministry of Defence.
The location, pinpointed through surveillance, was thought to be housing weapons and explosive materials, the announcement noted, and was located in mountainous terrain just above the historic site of Palmyra in the heart of Syria.
"Our aircraft utilized laser-guided Paveway IV weapons to target a number of approach shafts leading to the site... preliminary assessments indicate the target was engaged successfully," the MoD said.
There was no sign of any civilian casualties in the strike conducted Saturday night and every plane involved made a safe return, the defence officials confirmed.
The British jets were assisted by a Voyager aerial refuelling aircraft.
Daesh - referred to as Daesh - enforced militant control over parts of Iraq and Syria before its territorial defeat in 2019.
"This action demonstrates our UK leadership, and determination to operate in unison with our partners, to eradicate any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," Britain's Defence Chief John Healey remarked.
RAF aircraft have conducted overwatch operations over Syria to "prevent any attempted resurgence" of IS following its defeat at the battle of Baghuz in 2019, the authorities noted.
"I extend gratitude to every member of the UK armed forces participating in this operation for their skill and their valour," the Defence Secretary said. "Including them were numerous British troops stationed over the holidays. This action, to take out terrorist threats who threaten our way of life, demonstrates how UK forces are ready to step up, continuously, protecting the UK domestically and strong abroad."
During December, the US military carried out what it called a "large-scale strike" on IS targets in Syria, subsequent to an assault claimed the lives of two US servicemembers and a local interpreter in the Palmyra area.
The U.N. reports IS still maintains roughly 5-7 thousand militants in Iraq and Syria.